Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 9-hydroxy-8-methoxy-6-nitro- - Names and Identifiers
Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 9-hydroxy-8-methoxy-6-nitro- - Physico-chemical Properties
Molecular Formula | C17H11NO8
|
Molar Mass | 357.27 |
Density | 1.656±0.06 g/cm3(Predicted) |
Melting Point | 267-269°C |
Boling Point | 663.7±55.0 °C(Predicted) |
Solubility | Soluble in ethanol, ethyl acetate, slightly soluble in petroleum ether, insoluble in water |
Appearance | Yellow-brown crystalline powder |
pKa | 2.94±0.20(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD03840549 |
Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 9-hydroxy-8-methoxy-6-nitro- - Introduction
7-hydroxyaristolochic acid A (7-hydroxyaristolochic acid A) is A natural organic acid, which belongs to the alkaloid composition in Aristolochia plants. Its molecular formula is C17H11NO7 and its molecular weight is 357.27g/mol. The following is A description of the properties, uses, preparation methods and safety information of 7-hydroxy aristolochic acid A:
Nature:
7-Hydroxyaristolochic acid A is A white to pale yellow crystalline solid, soluble in water and ethanol. It is strongly toxic and has a serious damaging effect on the kidneys and reproductive system.
Use:
7-Hydroxyaristolochic acid A is widely used in traditional Chinese medicine, mainly for the treatment of certain inflammatory diseases and tumors. However, its use is currently not recommend due to its toxic effects.
Method:
7-hydroxy aristolochic acid A can be extracted from some aristolochaceae plants, can also be obtained through chemical synthesis. At present, it is generally not recommend to extract from natural plants, but to obtain high purity compounds by organic synthesis.
Safety Information:
7-hydroxyaristolochic acid A has high toxicity, has serious damage to the kidney and reproductive system, and has been proved to be related to the occurrence of renal cancer. Therefore, long-term or high-dose exposure to 7-hydroxyaristolochic acid A may cause serious health problems. In view of its toxicity, many countries have banned the use or sale of products containing 7-hydroxyaristolochic acid A, which should be used with caution to ensure human safety.
Last Update:2024-04-10 22:29:15